The Breakthrough Challenge
We raise funds to support breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center (ACC). Founded in 2013, the Breakthrough Challenge unites patients, researchers, their families, and friends for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley. To date, the Breakthrough Challenge has donated over $3.1 million dollars to the ACC, funding 74 research projects. 100% of all participant-raised dollars are donated directly to cancer research.
Our 2026 Fundraising Goal
$127,665
Raised of $300,000
Congratulations, Breakthrough Challenge!
You met the match and raised over $100,000 in less than two weeks. The total amount raised stands at $126,659 and counting!
Please keep at it; every dollar raised goes directly to fund breakthrough cancer research at Penn Medicine's Abramson Cancer Center.
THANK YOU TO OUR MATCH CHALLENGE PARTNER,
The Zent Family Foundation
Our 2025 Event Raised $350K!
Our Leaderboards
Top Fundraisers
Top Individuals (159)
View AllDavid Wellborn
$15,150.00 raised of $15,000.00
Bo Ebby
$10,950.00 raised of $15,000.00
Bruce Levine
$6,000.00 raised of $30,000.00
Franki Frank
$5,300.00 raised of $2,500.00
Top Teams (21)
View AllKeystone State Ride
$58,151.60 raised of $60,000.00
Team BC
$16,375.00 raised of $25,000.00
CARs Pedaling For Cures
$7,946.00 raised of $30,000.00
DTeam
$7,126.00 raised of $10,000.00
Team Zayde
$7,022.00 raised of $18,000.00
Donate To an Indvidual or a Team
Donate NowBreakthroughs in Action
Join Us to Make a Difference!