The Breakthrough Challenge
We raise funds to support breakthroughs in cancer research at Penn Medicine's Abramson Cancer Center (ACC). Founded in 2013, the Breakthrough Challenge unites patients, researchers, their families, and friends for a scenic and inspiring bike ride through Eastern PA's beautiful Oley Valley. To date, the Breakthrough Challenge has donated $2,825,000 to the ACC, funding 63 research projects. 100% of all participant-raised dollars are donated directly to cancer research.
Oue 2025 Ride
Save the Date!
Sunday, September 14, 2025
Breakthroughs in Action
Join Us for a Virtual Panel Discussion featuring Scientists Funded by the Breakthrough Challenge
Tuesday, May 6, 2025
1 – 2 PM
Learn about advancements being made in cancer research at Penn Medicine’s Abramson Cancer Center. Robert H. Vonderheide, MD, DPhil, Director, Penn Medicine’s Abramson Cancer Center, will moderate the panel discussion.
This progress is made possible through the incredible support of our Breakthrough Challenge community.
Our 2025 Fundraising Goal
$10,950
Raised of $300,000
Thank You To Our Fundraisers!
Top Individuals
View AllDrew Costello
$5,050.00 raised of $500.00
Richard Adler
$2,550.00 raised
Christopher Hall
$1,050.00 raised of $1,000.00
Ernie Tracy
$350.00 raised of $7,500.00
Top Teams
View AllTracy Breakthrough Riders
$400.00 raised of $10,000.00
Team Zayde
$300.00 raised of $18,000.00
Beam of Life
$300.00 raised of $10,000.00